Glycation-mediated inter-protein cross-linking is promoted by chaperone–client complexes of α-crystallin: Implications for lens aging and presbyopia

Author:

Nandi Sandip K.ORCID,Nahomi Rooban B.ORCID,Rankenberg Johanna,Glomb Marcus A.ORCID,Nagaraj Ram H.ORCID

Funder

HHS | National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference58 articles.

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2. Tryptophan and non-tryptophan fluorescence of the eye lens proteins provides diagnostics of cataract at the molecular level;Gakamsky;Sci. Rep,2017

3. Age-dependent deamidation of lifelong proteins in the human lens;Hains;Invest. Ophthalmol. Vis. Sci,2010

4. Racemisation and human cataract. d-Ser, d-Asp/Asn and d-Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lenses;Hooi;Age,2011

5. Characterization of disulfide-linked crystallins associated with human cataractous lens membranes;Kodama;Invest. Ophthalmol. Vis. Sci,1988

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