Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly-Reference-Cited by-同舟云学术

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Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly

Published:2017-03 Issue:12 Volume:292 Page:4766-4769
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

ElAzzouny Mahmoud,Tom Christopher T.M.B.,Evans Charles R.,Olson Lori L.,Tanga Mary J.,Gallagher Katherine A.,Martin Brent R.,Burant Charles F.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference17 articles.

1. Itaconic acid is a mammalian metabolite induced during macrophage activation;Strelko;J. Am. Chem. Soc,2011

2. Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production;Michelucci;Proc. Natl. Acad. Sci. U.S.A,2013

3. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization;Jha;Immunity,2015

4. Succinate is an inflammatory signal that induces IL-1α through HIF-1α;Tannahill;Nature,2013

5. Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels;Cordes;J. Biol. Chem,2016

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1. Differential effects of itaconate and its esters on the glutathione and glucose metabolism of cultured primary rat astrocytes;2024-09-09

2. Toward decoding spatiotemporal signaling activities of reactive immunometabolites with precision immuno-chemical biology tools;Communications Chemistry;2024-09-02

3. The anti-inflammatory effects of itaconate and its derivatives in neurological disorders;Cytokine & Growth Factor Reviews;2024-08

4. Itaconate suppresses house dust mite-induced allergic airways disease and Th2 cell differentiation;Mucosal Immunology;2024-08

5. Itaconate in host inflammation and defense;Trends in Endocrinology & Metabolism;2024-07

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