A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase-Reference-Cited by-同舟云学术

A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase

Published:2014-09 Issue:38 Volume:289 Page:26430-26440
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Shkriabai Nikoloz,Dharmarajan Venkatasubramanian,Slaughter Alison,Kessl Jacques J.,Larue Ross C.,Feng Lei,Fuchs James R.,Griffin Patrick R.,Kvaratskhelia Mamuka

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference56 articles.

1. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells;Cherepanov;J. Biol. Chem,2003

2. A role for LEDGF/p75 in targeting HIV DNA integration;Ciuffi;Nat. Med,2005

3. An essential role for LEDGF/p75 in HIV integration;Llano;Science,2006

4. LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration;Shun;Genes Dev,2007

5. Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration;Ferris;Proc. Natl. Acad. Sci. U.S.A,2010

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Optimizing the Multimerization Properties of Quinoline-Based Allosteric HIV-1 Integrase Inhibitors;Viruses;2024-01-28

2. The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir;2024-01-26

3. Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity;Molecules;2023-09-19

4. Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 Å resolution: Routes to inhibitor optimization;PLOS Pathogens;2023-03-03

5. Multi-Substituted Quinolines as HIV-1 Integrase Allosteric Inhibitors;Viruses;2022-07-02