Multiple Propofol-binding Sites in a γ-Aminobutyric Acid Type A Receptor (GABAAR) Identified Using a Photoreactive Propofol Analog

Author:

Jayakar Selwyn S.,Zhou Xiaojuan,Chiara David C.,Dostalova Zuzana,Savechenkov Pavel Y.,Bruzik Karol S.,Dailey William P.,Miller Keith W.,Eckenhoff Roderic G.,Cohen Jonathan B.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference46 articles.

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3. General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor β3 subunit;Jurd;FASEB J,2003

4. General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal;Franks;Nat. Rev. Neurosci,2008

5. Binding, activation and modulation of Cys-loop receptors;Miller;Trends Pharmacol. Sci,2010

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