Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule-Reference-Cited by-同舟云学术

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Published:2015-01 Issue:2 Volume:290 Page:762-774
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Deng Gejing,Shen Junqing,Yin Ming,McManus Jessica,Mathieu Magali,Gee Patricia,He Timothy,Shi Chaomei,Bedel Olivier,McLean Larry R.,Le-Strat Frank,Zhang Ying,Marquette Jean-Pierre,Gao Qiang,Zhang Bailin,Rak Alexey,Hoffmann Dietmar,Rooney Eamonn,Vassort Aurelie,Englaro Walter,Li Yi,Patel Vinod,Adrian Francisco,Gross Stefan,Wiederschain Dmitri,Cheng Hong,Licht Stuart

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

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4. IDH mutations in glioma and acute myeloid leukemia;Dang;Trends Mol. Med,2010

5. The human PICD gene encodes a cytoplasmic and peroxisomal NADP+-dependent isocitrate dehydrogenase;Geisbrecht;J. Biol. Chem,1999

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