pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference41 articles.
1. Abnormally short serum half-lives of IgG in β2-microglobulin-deficient mice;Ghetie;Eur. J. Immunol,1996
2. Multiple roles for the major histocompatibility complex class I-related receptor FcRn;Ghetie;Annu. Rev. Immunol,2000
3. Increased clearance of IgG in mice that lack β2-microglobulin: possible protective role of FcRn;Israel;Immunology,1996
4. Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn;Kim;Eur. J. Immunol,1999
5. Crystal structure at 2.8 angstrom of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding;Martin;Mol. Cell,2001
Cited by 83 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies;Journal of Pharmaceutical Sciences;2024-09
2. In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection;Molecular Therapy;2024-08
3. Assessment and incorporation of in vitro correlates to pharmacokinetic outcomes in antibody developability workflows;mAbs;2024-07-31
4. Rapid depletion of “catch-and-release” anti-ASGR1 antibody in vivo;mAbs;2024-07-25
5. Comprehensive approaches to preclinical evaluation of monoclonal antibodies and their next-generation derivatives;Biochemical Pharmacology;2024-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3