A Molecular Docking Strategy Identifies Eosin B as a Non-active Site Inhibitor of Protozoal Bifunctional Thymidylate Synthase-Dihydrofolate Reductase-Reference-Cited by-同舟云学术

A Molecular Docking Strategy Identifies Eosin B as a Non-active Site Inhibitor of Protozoal Bifunctional Thymidylate Synthase-Dihydrofolate Reductase

Published:2003-04 Issue:16 Volume:278 Page:14092-14100
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Atreya Chloé E.,Johnson Eric F.,Irwin John J.,Dow Antonia,Massimine Kristen M.,Coppens Isabelle,Stempliuk Valeska,Beverley Stephen,Joiner Keith A.,Shoichet Brian K.,Anderson Karen S.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference37 articles.

1. Structure of and kinetic channelling in bifunctional dihydrofolate reductase–thymidylate synthase

2. Substrate Channeling and Domain−Domain Interactions in Bifunctional Thymidylate Synthase−Dihydrofolate Reductase

3. A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase11Edited by R. Huber

4. Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase.

5. Flexible ligand docking using conformational ensembles

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