Normalization of Cholesterol Homeostasis by 2-Hydroxypropyl-β-cyclodextrin in Neurons and Glia from Niemann-Pick C1 (NPC1)-deficient Mice
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference26 articles.
1. Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis;Carstea;Science,1997
2. Identification of HE1 as the second gene of Niemann-Pick C disease;Naureckiene;Science,2000
3. Niemann-Pick disease type C;Vanier;Clin. Genet.,2003
4. Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes;Wang;Cell Metab.,2010
5. The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells;Wojtanik;J. Biol. Chem.,2003
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1. Lysosomal cholesterol accumulation is commonly found in most peroxisomal disorders and reversed by 2-hydroxypropyl-β-cyclodextrin;Science China Life Sciences;2023-03-23
2. Intravenous 2-hydroxypropyl-β-cyclodextrin (Trappsol® Cyclo™) demonstrates biological activity and impacts cholesterol metabolism in the central nervous system and peripheral tissues in adult subjects with Niemann-Pick Disease Type C1: Results of a phase 1 trial;Molecular Genetics and Metabolism;2022-12
3. Cyclodextrins applied to the treatment of lysosomal storage disorders;Advanced Drug Delivery Reviews;2022-12
4. Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?;Pharmaceutics;2022-11-22
5. Effects of 6-O-α-maltosyl-β cyclodextrin on lipid metabolism in Npc1-deficient Chinese hamster ovary cells;Molecular Genetics and Metabolism;2022-11
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