Aberrant Epigenetic and Genetic Marks Are Seen in Myelodysplastic Leukocytes and Reveal Dock4 as a Candidate Pathogenic Gene on Chromosome 7q-Reference-Cited by-同舟云学术

Aberrant Epigenetic and Genetic Marks Are Seen in Myelodysplastic Leukocytes and Reveal Dock4 as a Candidate Pathogenic Gene on Chromosome 7q

Published:2011-07 Issue:28 Volume:286 Page:25211-25223
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Zhou Li,Opalinska Joanna,Sohal Davendra,Yu Yiting,Mo Yongkai,Bhagat Tushar,Abdel-Wahab Omar,Fazzari Melissa,Figueroa Maria,Alencar Cristina,Zhang Jinghang,Kambhampati Suman,Parmar Simrit,Nischal Sangeeta,Hueck Christoph,Suzuki Masako,Freidman Ellen,Pellagatti Andrea,Boultwood Jacqueline,Steidl Ulrich,Sauthararajah Yogen,Yajnik Vijay,Mcmahon Christine,Gore Steven D.,Platanias Leonidas C.,Levine Ross,Melnick Ari,Wickrema Amittha,Greally John M.,Verma Amit

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference45 articles.

1. Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients

2. Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype

3. The fundamental role of epigenetic events in cancer

4. Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia

5. Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients

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