Engineering of a Single Conserved Amino Acid Residue of Herpes Simplex Virus Type 1 Thymidine Kinase Allows a Predominant Shift from Pyrimidine to Purine Nucleoside Phosphorylation-Reference-Cited by-同舟云学术

Engineering of a Single Conserved Amino Acid Residue of Herpes Simplex Virus Type 1 Thymidine Kinase Allows a Predominant Shift from Pyrimidine to Purine Nucleoside Phosphorylation

Published:2006-07 Issue:28 Volume:281 Page:19273-19279
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Balzarini Jan,Liekens Sandra,Solaroli Nicola,El Omari Kamel,Stammers David K.,Karlsson Anna

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference16 articles.

1. Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy.

2. Enhancement of tumor ablation by a selected HSV-1 thymidine kinase mutant

3. Characterization of Herpes Simplex Virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity

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