A Loss of Function Mutation of Presenilin-2 Interferes with Amyloid β-Peptide Production and Notch Signaling-Reference-Cited by-同舟云学术

A Loss of Function Mutation of Presenilin-2 Interferes with Amyloid β-Peptide Production and Notch Signaling

Published:1999-10 Issue:40 Volume:274 Page:28669-28673
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Steiner Harald,Duff Karen,Capell Anja,Romig Helmut,Grim Melissa G.,Lincoln Sarah,Hardy John,Yu Xin,Picciano Melanie,Fechteler Katja,Citron Martin,Kopan Raphael,Pesold Brigitte,Keck Simone,Baader Miriam,Tomita Taisuke,Iwatsubo Takeshi,Baumeister Ralf,Haass Christian

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference36 articles.

1. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

2. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

3. Skeletal and CNS Defects in Presenilin-1-Deficient Mice

4. Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

5. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Cited by 290 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The pathogenicity ofPSEN2variants is tied to Aβ production and homology toPSEN1;2024-06-28

2. Using Drosophila amyloid toxicity models to study Alzheimer's disease;Annals of Human Genetics;2024-03-22

3. Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy;iScience;2024-01

4. Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by γ-Secretase;Journal of Molecular Biology;2023-09

5. Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site;Communications Biology;2023-06-24