Runx1 Phosphorylation by Src Increases Trans-activation via Augmented Stability, Reduced Histone Deacetylase (HDAC) Binding, and Increased DNA Affinity, and Activated Runx1 Favors Granulopoiesis-Reference-Cited by-同舟云学术

Runx1 Phosphorylation by Src Increases Trans-activation via Augmented Stability, Reduced Histone Deacetylase (HDAC) Binding, and Increased DNA Affinity, and Activated Runx1 Favors Granulopoiesis

Published:2016-01 Issue:2 Volume:291 Page:826-836
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Leong Wan Yee,Guo Hong,Ma Ou,Huang Hui,Cantor Alan B.,Friedman Alan D.

Funder

National Institutes of Health

Gabrielle's Angel Foundation

Giant Food Children's Cancer Research Fund

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference40 articles.

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3. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype;Growney;Blood,2005

4. Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis;Guo;Blood,2012

5. PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis;Huang;Nat. Genet,2008

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5. RUNX1 Dosage in Development and Cancer;MOL CELLS;2020