Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ
Author:
Funder
National Institute of General Medical Sciences
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference37 articles.
1. Conotoxin gene superfamilies;Robinson;Mar. Drugs,2014
2. Specificity, affinity and efficacy of ι-conotoxin RxIA, an agonist of voltage-gated sodium channels NaV1.2, 1.6 and 1.7;Fiedler;Biochem. Pharmacol,2008
3. μO-conotoxins inhibit NaV channels by interfering with their voltage sensors in domain-2;Leipold;Channels,2007
4. A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ;Gajewiak;Proc. Natl. Acad. Sci. U.S.A,2014
5. Probing the redox states of sodium channel cysteines at the binding site of μO§-conotoxin GVIIJ;Zhang;Biochemistry,2015
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