Functional Expression of the Chicken Low Density Lipoprotein Receptor-related Protein in a Mutant Chinese Hamster Ovary Cell Line Restores Toxicity of Pseudomonas Exotoxin A and Degradation of α2-Macroglobulin-Reference-Cited by-同舟云学术

Functional Expression of the Chicken Low Density Lipoprotein Receptor-related Protein in a Mutant Chinese Hamster Ovary Cell Line Restores Toxicity of Pseudomonas Exotoxin A and Degradation of α2-Macroglobulin

Published:1998-03 Issue:11 Volume:273 Page:6057-6065
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Avramoglu Rita Kohen,Nimpf Johannes,McLeod Roger S.,Ko Kerry W.S.,Wang Yuwei,FitzGerald David,Yao Zemin

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference39 articles.

1. The somatic cell-specific low density lipoprotein receptor-related protein of the chicken. Close kinship to mammalian low density lipoprotein receptor gene family members.

2. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.

3. Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment.

4. The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro

5. 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein.

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