Expression of Multidrug Resistance Protein/GS-X Pump and γ-Glutamylcysteine Synthetase Genes Is Regulated by Oxidative Stress
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
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2. Function, evolution and structure of multidrug resistance protein (MRP)
3. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
4. Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
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