EDG1 Is a Functional Sphingosine-1-phosphate Receptor That Is Linked via a Gi/o to Multiple Signaling Pathways, Including Phospholipase C Activation, Ca2+Mobilization, Ras-Mitogen-activated Protein Kinase Activation, and Adenylate Cyclase Inhibition-Reference-Cited by-同舟云学术

EDG1 Is a Functional Sphingosine-1-phosphate Receptor That Is Linked via a Gi/o to Multiple Signaling Pathways, Including Phospholipase C Activation, Ca2+Mobilization, Ras-Mitogen-activated Protein Kinase Activation, and Adenylate Cyclase Inhibition

Published:1998-10 Issue:42 Volume:273 Page:27104-27110
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Okamoto Hiroyuki,Takuwa Noriko,Gonda Koichi,Okazaki Hiroshi,Chang Kuyngho,Yatomi Yutaka,Shigematsu Hiroshi,Takuwa Yoh

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference32 articles.

1. Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines

2. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation.

3. The sphingomyelin cycle and the second messenger function of ceramide.

4. Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness.

5. Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.

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