The Role of Factor XIa (FXIa) Catalytic Domain Exosite Residues in Substrate Catalysis and Inhibition by the Kunitz Protease Inhibitor Domain of Protease Nexin 2
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference54 articles.
1. Human blood coagulation factor XI. Purification, properties, and mechanism of activation by activated factor XII.
2. Association of factor XI and high molecular weight kininogen in human plasma.
3. The Mode of Inheritance of PTA Deficiency: Evidence for the Existence of Major PTA Deficiency and Minor PTA Deficiency
4. Heredity and Coagulation Studies in Ten Families with Factor XI (Plasma Thromboplastin Antecedent) Deficiency
5. Activation of human blood coagulation factor XI independent of factor XII.
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1. Dual Inhibition of Factor XIIa and Factor XIa Produces a Synergistic Anticoagulant Effect;Journal of Cardiovascular Pharmacology;2024-07
2. Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant;Frontiers in Cardiovascular Medicine;2021-03-19
3. Chemical Footprinting Reveals Conformational Changes Following Activation of Factor XI;Thrombosis and Haemostasis;2018
4. A Sequential Mechanism for Exosite-mediated Factor IX Activation by Factor XIa;Journal of Biological Chemistry;2012-11
5. The prohormone proenkephalin possesses differential conformational features of subdomains revealed by rapid H-D exchange mass spectrometry;Protein Science;2012-01-04
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