Putative Role of the Orphan Nuclear Receptor SXR (Steroid and Xenobiotic Receptor) in the Mechanism of CYP3A4 Inhibition by Xenobiotics
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference36 articles.
1. IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A
2. An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway
3. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
4. SXR, a novel steroid and xenobioticsensing nuclear receptor
5. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
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