The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites
Author:
Funder
HHS | NIH | National Cancer Institute
HHS | NIH | National Institute of Environmental Health Sciences
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference93 articles.
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2. MUTYH-associated polyposis–from defect in base excision repair to clinical genetic testing;Cheadle;DNA Repair,2007
3. Base-excision repair of oxidative DNA damage;David;Nature,2007
4. Repair of 8-oxoG:A mismatches by the MUTYH glycosylase: mechanism, metals and medicine;Banda;Free Radic. Biol. Med,2017
5. MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA;Markkanen;Front. Genet,2013
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2. Biochemical analysis of H2O2-induced mutation spectra revealed that multiple damages were involved in the mutational process;DNA Repair;2024-02
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4. APE1-dependent base excision repair of DNA photodimers in human cells;Molecular Cell;2023-10
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