SMAD family member 3 (SMAD3) and SMAD4 repress HIF2α-dependent iron-regulatory genes

Author:

Ma Xiaoya,Das Nupur K.,Castillo Cristina,Gourani Ayla,Perekatt Ansu O.,Verzi Michael P.,Shah Yatrik M.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference49 articles.

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2. The impact of O2 availability on human cancer;Bertout;Nat. Rev. Cancer,2008

3. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects;Höckel;J. Natl. Cancer Inst,2001

4. The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy;Muz;Hypoxia,2015

5. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation;Semenza;Mol. Cell Biol,1992

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