The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential-Reference-Cited by-同舟云学术

The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential

Published:2004-06 Issue:24 Volume:279 Page:25689-25695
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Orsini Francesca,Migliaccio Enrica,Moroni Maurizio,Contursi Cristina,Raker Veronica A.,Piccini Daniele,Martin-Padura Ines,Pelliccia Giovanni,Trinei Mirella,Bono Maria,Puri Claudia,Tacchetti Carlo,Ferrini Monica,Mannucci Roberta,Nicoletti Ildo,Lanfrancone Luisa,Giorgio Marco,Pelicci Pier Giuseppe

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference30 articles.

1. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

2. Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway

3. The p66shc adaptor protein controls oxidative stress response and life span in mammals

4. Genetic pathways that regulate ageing in model organisms

5. A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis

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