Expression, Refolding, and Autocatalytic Proteolytic Processing of the Interleukin-1β-converting Enzyme Precursor-Reference-Cited by-同舟云学术

Expression, Refolding, and Autocatalytic Proteolytic Processing of the Interleukin-1β-converting Enzyme Precursor

Published:1995-04 Issue:16 Volume:270 Page:9378-9383
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Ramage Paul,Cheneval Dominique,Chvei Maria,Graff Patrick,Hemmig Rene,Heng Richard,Kocher Hans Peter,Mackenzie Andrew,Memmert Klaus,Revesz Laszlo,Wishart William

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference21 articles.

1. The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.

2. Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.

3. Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

4. Purification and Characterization of Human Recombinant Precursor Interleukin 1 β

5. Activation of interleukin- 1β by a co-induced protease

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