An Anti-CD3 Single-chain Immunotoxin with a Truncated Diphtheria Toxin Avoids Inhibition by Pre-existing Antibodies in Human Blood
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference24 articles.
1. Characterization of single-chain antibody (sFv)-toxin fusion proteins produced in vitro in rabbit reticulocyte lysate.
2. Immunotoxins for in Vivo Therapy: Where Are We?
3. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein
4. A Point Mutation of Proline 308 in Diphtheria Toxin B Chain Inhibits Membrane Translocation of Toxin Conjugates
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2. CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells;Frontiers in Immunology;2022-10-26
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5. A deimmunised form of the ribotoxin, α-sarcin, lacking CD4+T cell epitopes and its use as an immunotoxin warhead;Protein Engineering Design and Selection;2016-08-29
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