Inactivation of the Intrinsic Activity of Pro-urokinase by Diisopropyl Fluorophosphate Is Reversible
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference15 articles.
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2. A proenzyme form of human urokinase.
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4. One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity.
5. Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu).
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1. Assays to quantify fibrinolysis: strengths and limitations. Communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee on fibrinolysis;Journal of Thrombosis and Haemostasis;2023-04
2. The Efficacy and Safety of Pharmacoinvasive Therapy with Prourokinase for Acute ST ‐Segment Elevation Myocardial Infarction Patients with Expected Long Percutaneous Coronary Intervention‐Related Delay;Cardiovascular Therapeutics;2013-09-12
3. Urokinase-An Important Anti-Thromboembolic Drug;Frontiers in Cardiovascular Drug Discovery;2012-03-26
4. Soluble expression of a strong thrombolytic pro-urokinase mutant in Escherichia coli;Protein Expression and Purification;2006-07
5. Each Lipase Has a Unique Sensitivity Profile for Organophosphorus Inhibitors;Toxicological Sciences;2006-01-31
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