Tyrosyl-DNA Phosphodiesterase I Catalytic Mutants Reveal an Alternative Nucleophile That Can Catalyze Substrate Cleavage-Reference-Cited by-同舟云学术

Tyrosyl-DNA Phosphodiesterase I Catalytic Mutants Reveal an Alternative Nucleophile That Can Catalyze Substrate Cleavage

Published:2015-03 Issue:10 Volume:290 Page:6203-6214
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Comeaux Evan Q.,Cuya Selma M.,Kojima Kyoko,Jafari Nauzanene,Wanzeck Keith C.,Mobley James A.,Bjornsti Mary-Ann,van Waardenburg Robert C.A.M.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference47 articles.

1. A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases;Yang;Proc. Natl. Acad. Sci. U.S.A,1996

2. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I;Hsiang;J. Biol. Chem,1985

3. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin;Hsiang;Cancer Res,1989

4. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs;Pommier;Chem. Biol,2010

5. DNA topoisomerases: harnessing and constraining energy to govern chromosome topology;Schoeffler;Q. Rev. Biophys,2008

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Zymolyase Treatment of Saccharomyces cerevisiae Affects Cellular Proteins and Degrades Tyrosyl-DNA Phosphodiesterase I;DNA and Cell Biology;2024-07-01

2. SCAN1 mutant TDP1 blocks the repair of DSB induced by TOP1 activity during gene transcription and promotes genome reorganisations and cell death in quiescent cells;2024-05-31

3. Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics;Nucleic Acids Research;2023-06-02

4. N-terminal domain of tyrosyl-DNA phosphodiesterase I regulates topoisomerase I-induced toxicity in cells;Scientific Reports;2023-01-25

5. Mechanistic Insight into AP-Endonuclease 1 Cleavage of Abasic Sites at Stalled Replication Forks;2022-08-22