5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

Author:

Prantner Daniel,Perkins Darren J.,Lai Wendy,Williams Mark S.,Sharma Shruti,Fitzgerald Katherine A.,Vogel Stefanie N.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference83 articles.

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3. Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice;Ching;Br. J. Cancer,2004

4. The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis;Roberts;J. Exp. Med.,2007

5. Activation of LPS-inducible genes by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid in primary murine macrophages. Dissection of signaling pathways leading to gene induction and tyrosine phosphorylation;Perera;J. Immunol.,1994

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