Difficulties of Differential Diagnosis of Hurthle Cell Thyroid Tumor

Author:

Danzanova T. Yu.1ORCID,Gudilina E. A.2ORCID,Kalinina A. A.2,Lepedatu P. I.2ORCID,Sinyukova G. T.2ORCID

Affiliation:

1. N.N. Blokhin National Medical Research Center of Oncology; N.I. Pirogov Russian National Research Medical University

2. N.N. Blokhin National Medical Research Center of Oncology

Abstract

Purpose: Assessment of the capabilities of the ultrasound method in the diagnostics of a rare Hurthle-cell tumor of the thyroid gland on the example of a clinical case of a patient with malignant neoplasms of independent primary multiple localizations in comparison with other research methods.Material and methods: A comprehensive study of materials from the history of the disease, the results of clinical, laboratory, instrumental, morphological research methods and their comparison with diagnostic cases from literature data.Results: Despite the full comprehensive examination of the patient, including ultrasound, MRI, PET/CT, puncture biopsy under ultrasound control, it was not possible to make the correct diagnosis before the operation. The presence of other malignant diseases in the patient’s history, the presence of altered paratracheal nodes in the same zone, and the rare occurrence of Hurthle thyroid tumors played a role.Conclusions: Hurthle-thyroid cell tumors are a rare disease, but it must always be taken into account in the diagnostic search, since even benign Hurthle tumors have a high risk of malignancy and spreading of distant metastases. 

Publisher

Non-profit partnership Society of Interventional Oncoradiologists

Reference10 articles.

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2. Kozykenova ZhU, Zhetpisbaev BA, Toktabaeva BZh, et al. Oncocytic variant of thyroid follicular tumors (literature review). Medicine (Almaty). 2016;11(173):60-4. (In Russian).

3. Severskaya NV, Ilyin AA, Chebotareva IV, et al. Oxyphil-cell tumors of the thyroid. Problems of Endocrinology. 2008;54(4):21-7. (In Russian). DOI:10.14341/probl20085442127.

4. Asa SL. My approach to oncocytic tumours of the thyroid. J Clinical Pathol. 2004;57(3):225-32. DOI: 10.1136/jcp.2003.008474.

5. Ponkina ON. Classification for Thyroid Gland Tumors (WHO, 2017): Attention to Prognostic Factors. Innovative Medicine of Kuban. 2017;8(4):53-9. (In Russian).

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