A Unique Case of Unilateral Synophthalmia

Author:

Proia Alan D.1

Affiliation:

1. Department of Pathology, Duke University Medical Center, Durham, NC, USA

Abstract

Developmental anomalies resulting in a single eye (cyclopia) or fusion of the eyes (synophthalmia) are rare. Examples of unilateral synophthalmia—in which there are 1 normal and 2 fused eyes from 3 anlagen in 2 orbits, 1 lateral proboscis, and 3 optic nerves—are even more rare. Herein, I report a unique fetus with unilateral synophthalmia that was not associated with a lateral proboscis but instead had an extra cerebral hemisphere. I postulate that the unilateral synophthalmia, accessory cerebral hemisphere, and minor structural abnormalities in the skull base were the result of failure in separating a monozygous twin, a situation similar to that postulated as the cause of fetus in fetu.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology and Child Health

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