Syringocystadenoma Papilliferum: A Rare Breast Tumor in a Young Boy

Author:

Vaos George1,Pierrakou Paraskevi2

Affiliation:

1. Department of Paediatric Surgery, Penteli General Children's Hospital, 8 Hippocratous Street, 15236 P. Penteli, Athens, Greece

2. Department of Pathology, Sismanoglio General Hospital, 1 Sismanogliou Street, 15126 Maroussi, Athens, Greece

Abstract

Syringocystadenoma papilliferum of the breast is extremely rare in children. However, some occasional cases have been diagnosed in females. This report documents a case of syringocystadenoma papilliferum occurring in a healthy 4-year-old male. Histopathologically, this tumor, located deep in the dermis, was characterized by the presence of papillary projections extending into the lumen of epithelial cystic invaginations in a background of dense fibrous tissue. The papillary projections and the duct-like structures were lined by an inner columnar epithelium, which demonstrated luminal apical decapitation secretion, and had an outer layer of smaller cuboidal cells. These findings support apocrine differentiation in this case. A fairly dense mononuclear infiltrate in the stroma of the tumor, especially in the papillary projections, was also present. Although syringocystadenoma papilliferum is rare in children, it should not be summarily ruled out during examinations of masses found in the pediatric male breast. It is important to recognize this unusual location of the tumor so that a prompt diagnosis, based on histopathology and surgical excision, can be proposed.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Apocrine and Eccrine Differentiation;International Journal of Molecular Sciences;2021-05-11

2. Syringocystadenoma papilliferum of the male nipple;Journal of Cutaneous Pathology;2016-05-18

3. Flesh-colored papule on the areola;International Journal of Dermatology;2013-10-25

4. Syringocystadenoma papilliferum on the male nipple;The Journal of Dermatology;2011-02-01

5. Papilla mammaria-like syringocystadenoma papilliferum on the neck;Journal of the European Academy of Dermatology and Venereology;2009-03

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