A Rare Association of Celiac Disease and Aplastic Anemia: Case Report of a Child and Review of Literature

Author:

Badyal Rama Kumari1,Sachdeva Man Updesh Singh1,Varma Neelam1,Thapa Babu Ram2

Affiliation:

1. Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

2. Department of Pediatric Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Abstract

An association between severe aplastic anemia and other autoimmune diseases is rare and has been described in adults for eosinophilic fasciitis, thymomas, systemic lupus erythematosus, and thyroid disorders. Herein we report a patient with celiac disease who was not strictly following a gluten-free diet and presented with progressive pallor, fever, and weakness of 1 month's duration. On investigation, he had pancytopenia, which on subsequent evaluation revealed aplastic anemia. An association between aplastic anemia and celiac disease has rarely been reported. To the best of author's knowledge, only 1 pediatric case of celiac disease associated with aplastic anemia has been published. This is the second report to suggest such an association in children.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology and Child Health

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