Ascending in Utero Herpes Simplex Virus Infection in an Initially Healthy-Appearing Premature Infant-Reference-Cited by-同舟云学术

Ascending in Utero Herpes Simplex Virus Infection in an Initially Healthy-Appearing Premature Infant

Published:2015-03 Issue:2 Volume:18 Page:155-158
ISSN:1093-5266
Container-title:Pediatric and Developmental Pathology
language:en
Short-container-title:Pediatr Dev Pathol

Author:

Edwards Morven S.¹,Popek Edwina J.²,Wise Brittany³,Hatzenbuehler Lindsay¹,Arunachalam Athis R.⁴,Hair Amy B.⁴

Affiliation:

1. Section of Infectious Disease, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA

2. Department of Pathology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA

3. Pediatric Residency Program of the Icahn School of Medicine at Mount Sinai, New York, NY, USA

4. Section of Neonatology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA

Abstract

The usual route of acquisition for intrauterine herpes simplex virus (HSV) infection is transplacental. We evaluated a premature infant with in utero acquisition of HSV resulting from ascending infection. Histopathologic evidence of chronic chorioamnionitis and positive staining with immunohistochemistry for HSV in the placenta and umbilical cord established the diagnosis. The clinical presentation was also of interest in that the infant was initially healthy appearing.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.2350/14-09-1548-CR.1

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