Congenital Intracranial Mesenchymal Chondrosarcoma: Case Report and Review of the Literature in Pediatric Patients

Author:

De Cecio Rossella1,Migliaccio Ilenia1,Falleti Jessica1,Del De Caro Marialaura Basso1,Pettinato Guido1

Affiliation:

1. Dipartimento di Scienze Biomorfologiche e Funzionali, Università degli Studi di Napoli, “Federico II,” Napoli, Italy

Abstract

In this paper we report the 1st case of a congenital intracranial mesenchymal chondrosarcoma in a 2-month-old infant, apparently present at birth. A magnetic resonance image showed a large left parietal solid mass, while microscopy revealed a mixture of undifferentiated small cells and mature hyaline cartilage islands, positive for vimentin, S-100, and CD99. A surgical excision was performed but the patient died after a few weeks as a result of a rapid relapse of the tumor. We also review the pediatric cases (in patients less than 20 years old) of extraskeletal (intracranial) mesenchymal chondrosarcomas of the literature, with a focus on the most recent cytogenetic and immunohistochemical studies.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

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