An 8-Year-Old Child with Malignant Deciduoid Mesothelioma of the Abdomen: Report of a Case and Review of the Literature

Author:

Wolff-Bar Meirav1,Dujovny Tal2,Vlodavsky Eugene3,Postovsky Sergey2,Morgenstern Sara1,Braslavsky Diana1,Nissan Aviram4,Steinberg Ran5,Feinmesser Meora1

Affiliation:

1. Department of Pathology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

2. Department of Pediatric Hematology and Oncology, Rambam Medical Center, Haifa, Israel

3. Department of Pathology, Rambam Medical Center, Haifa, Israel

4. Department of Surgical Oncology, Chaim Sheba Medical Center, Tel Hashomer, Israel

5. Department of Surgery, Rambam Medical Center, Haifa, Israel

Abstract

Malignant mesothelioma is an uncommon tumor that usually arises in the pleural cavity of adults with a history of asbestos exposure. Less frequently, it appears in the peritoneum or other mesothelial surfaces. Deciduoid mesothelioma is a rare subtype that has been found at both sites. Of the 3 reported cases in children, 2 originated in the mesenterium and 1 in the pleura. We describe a 4th case of pediatric, malignant, deciduoid mesothelioma and a third case in the mesenteric cavity. The patient was an 8-year-old girl who presented with abdominal pain and fullness. Workup revealed extensive involvement of the abdomen by a serosa-based tumor. The clinical and pathologic findings are described, and the pertinent literature is reviewed.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

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1. Comprehensive genomic profiling of pediatric peritoneal mesothelioma: case report with a literature review;Journal of Surgical Case Reports;2024-05

2. Mesotheliomas in Children;Advances in Anatomic Pathology;2023-05-22

3. Pediatric Mesothelioma With ALK Fusions;American Journal of Surgical Pathology;2021-01-04

4. Multicystic and diffuse malignant peritoneal mesothelioma in children;Pediatric Blood & Cancer;2020-04-11

5. Gastrointestinal Tract;Pathology of Childhood and Adolescence;2020

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