Abstract
The present investigation was aimed to identify the potentiality of <i>Euphorbia thymifolia</i> Linn. and <i>Euphorbia hirta</i> Linn. leaf extract on the toxin-induced (carbon tetrachloride - CCl<sub>4</sub>) Albino Wistar rats. The animals were grouped into 7 categories including control (basal diet, G1), CCl<sub>4</sub>-induced (1.5 mL/kg, b.w., i.p.) (G2), G1 administrated with 300 mg/kg b.w., extract of <i>E. thymifolia</i> (G3) and <i>E. hirta</i> (G4), G2 administrated with 300 mg/kg b.w., extract of <i>E. thymifolia</i> (G5), <i>E. hirta</i> (G6), and standard drug (silymarin 25 mg/kg b.w.; G7) for 21-days trial period with each group contains 6 rats. The samples were collected and the following parameters including mitochondrial enzymes, different ATPase and lipid profiles were analyzed. The membrane-bound enzymes, the mitochondrial enzymes levels and the lipid profiles were reduced in the toxin-induced rats but the levels of enzymes were restored, significantly increased and lipid profiles are returned to the normal in the treatment of both extracts.
Reference44 articles.
1. Ahsan, M.R., Islam, K.M., Bulbul, I.J., 2009. Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachloride-induced hepatotoxicity in rats. Global Journal of Pharmacology. 3, 116–122.
2. Al-Assaf, A.H., 2014. Efficacy of corosolic acid on mitochondrial enzymes and DNA damage against CCl4-induced hepatotoxic rats. Journal of Animal and Plant Sciences. 24(5), 1366–1373.
3. A Spatial-Temporal Model of Cell Activation
4. Enzymatic Determination of Total Serum Cholesterol
5. Redeeming Measure of Atorvastatin in the Risk Factors of Cardiovascular Disease
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献