Subarachnoid hemorrhage during chemotherapy with ramucirumab: A case report
Author:
Affiliation:
1. Department of Neurosurgery, Toyohashi Medical Center
2. Department of Neurosurgery, Gifu Prefectural Gero Hospital
Publisher
Japan Stroke Society
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/jstroke/42/3/42_10703/_pdf
Reference6 articles.
1. 1) Auer TA, Renovanz M, Marini F, et al: Ischemic stroke and intracranial hemorrhage in patients with recurrent glioblastoma multiforme, treated with bevacizumab. J Neurooncol 133: 571–579, 2017
2. 2) Arnold D, Fuchs CS, Tabernero J, et al: Meta-analysis of individual patient safety data from six randomized, placebo-controlled trials with the antiangiogenic VEGFR2-binding monoclonal antibody ramucirumab. Ann Oncol 28: 2932–2942, 2017
3. 3) Shitara K, Muro K, Shimada Y, et al: Subgroup analyses of the safety and efficacy of ramucirumab in Japanese and Western patients in RAINBOW: a randomized clinical trial in second-line treatment of gastric cancer. Gastric Cancer 19: 927–938, 2016
4. 4) Xiao B, Wang W, Zhang D: Risk of bleeding associated with antiangiogenic monoclonal antibodies bevacizumab and ramucirumab: a meta-analysis of 85 randomized controlled trials. Onco Targets Ther 21: 5059–5074, 2018
5. 5) Tian R, Yan H, Zhang F, et al: Incidence and relative risk of hemorrhagic events associated with ramucirumab in cancer patients: a systematic review and meta-analysis. Oncotarget 7: 66182–66191, 2016
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