Sparse Lissajous scanning reflectance confocal microscope with an adjustable field of view and fast iterative Fourier filtering reconstruction

Abstract

Medical imaging devices are becoming increasingly compact, necessitating optimization research into different methods of actuation. Actuation influences important parameters of the imaging device such as size, weight, frame rate, field of view (FOV), and image reconstruction for imaging devices point scanning techniques. Current literature around piezoelectric fiber cantilever actuators focuses on device optimization with a fixed FOV but neglects adjustability. In this paper, we introduce an adjustable FOV piezoelectric fiber cantilever microscope and provide a characterization and optimization procedure. To overcome calibration challenges, we utilize a position sensitive detector (PSD) and address trade-offs between FOV and sparsity with a novel inpainting technique. Our work demonstrates the potential for scanner operation when sparsity and distortion dominate the FOV, extending the usable FOV for this form of actuation and others that currently only operate under ideal imaging conditions.