Volumetrically tracking retinal and choroidal structural changes in central serous chorioretinopathy

Author:

Wang Bingjie1ORCID,Brown Richard1,Chhablani Jay1,Pi Shaohua1ORCID

Affiliation:

1. University of Pittsburgh

Abstract

Central serous chorioretinopathy (CSCR) leads to the accumulation of subretinal fluid and retinal thickness change, which can be readily detected in clinics using optical coherence tomography (OCT). However, current quantification methods usually require sophisticated processing such as retinal layer segmentations, and volumetric visualization of structural changes is generally challenging, which can hinder fast and accurate assessment of disease progression and/or treatment efficacy. In this study, we developed an algorithm that can register the OCT scans acquired from different visits without requiring prior layer segmentation and calculated the three-dimensional (3-D) structural change maps for patients with CSCR. Our results demonstrate that this tool can be useful in monitoring the progression of CSCR and revealing the resolution of pathologies following treatment automatically with minimal pre-processing.

Funder

Research to Prevent Blindness

Eye & Ear Foundation of Pittsburgh

Alcon Research Institute

Knights Templar Eye Foundation

National Eye Institute

Publisher

Optica Publishing Group

Subject

Atomic and Molecular Physics, and Optics,Biotechnology

Reference33 articles.

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Central Serous Chorioretinopathy: Pathogenesis and Management

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