Affiliation:
1. University of Montreal
2. Research Center
3. Institute of Biomedical Engineering
4. Castor Optics
Abstract
Here, we present MCOCT, a Monte Carlo simulator for optical coherence tomography (OCT), incorporating a Gaussian illumination scheme and bias to increase backscattered event collection. MCOCT optical fluence was numerically compared and validated to an established simulator (MCX) and showed concordance at the focus while diverging slightly with distance to it. MCOCT OCT signals were experimentally compared and validated to OCT signals acquired in tissue-mimicking phantoms with known optical properties and showed a similar attenuation pattern with increasing depth while diverging beyond 1.5 mm and proximal to layer interfaces. MCOCT may help in the design of OCT systems for a wide range of applications.
Funder
Deutscher Akademischer Austauschdienst
Natural Sciences and Engineering Research Council of Canada
Subject
Atomic and Molecular Physics, and Optics,Biotechnology