Abstract
A spatially weighted filter applied to both the measurement and the Jacobian is proposed for high-density diffuse correlation tomography (DCT) to remove unwanted extracerebral interferences and artefacts along with better depth localization in the reconstructed blood flow images. High-density DCT is implemented by appropriate modification of recently introduced Multi-speckle Diffuse Correlation Spectroscopy (M-DCS) system. Additionally, we have used autocorrelation measurements at multiple delay-times in an iterative manner to improve the reconstruction results. The proposed scheme has been validated by simulations, phantom experiments and in-vivo human experiments.
Funder
Wadhwani Research Centre for Bioengineering (WRCB), Indian Institute of Technology Bombay
Department of Biotechnology, Ministry of Science and Technology, India
Department of Science and Technology, Ministry of Science and Technology, India
Indian Institute of Technology Bombay
Subject
Atomic and Molecular Physics, and Optics,Biotechnology
Cited by
5 articles.
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