Author:
Bruulsema J. T.,Essenpreis M.,Heinemann L.,Hayward J. E.,Berger M.,Gries F. A.,Koschinsky T.,Sandahl-Christiansen J.,Orskov H.,Farrell T. J.,Patterson M. S.,Böcker D.
Abstract
Diabetics would benefit from a device capable of providing continuous non-invasive monitoring of their blood glucose levels. A feasibility study was performed to determine whether a technique applying spatially resolved diffuse reflectance measurements could be used to detect changes in the blood glucose levels of diabetic volunteers by monitoring the tissue reduced scattering coefficient. A correlation was observed between step changes in blood glucose concentration and tissue reduced scattering coefficient in 17 out of 22 subjects. A study on non-diabetic volunteers was used to estimate the physiological baseline noise level.