Author:
Grier David G.,Quddus Rushna,Snyder Kaitlynn,Altman Lauren E.,Kirshenbaum Kent
Abstract
Holographic particle characterization yields the diameter of individual colloidal spheres with nanometer precision and can resolve probe beads growing as molecules bind to their surfaces. We demonstrate label-free holographic assays for antibodies and for antigenic proteins from pathogenic viruses, including SARS-CoV-2 and H1N1.