Abstract
With the establishment of
validity using authoritative
experimental results, an analytical investigation of an SPR-based
fiber optic sensor, employing a wave-theory-based technique for
determining breast cancer by shining a radially polarized Bessel–Gauss
(RPBG) beam, is proposed. First, by using a radially polarized
Gaussian (RPG) beam, the observed sensitivity is
9404.61 dB/RIU, where the acquired results are in good
concurrence with the experimental data reported by Yan et al. [Chin. Opt. Lett.
7, 909 (2009)COLHBT1671-7694]. Thus, the
proposed theory has been validated with the reported experimental
data. This theoretical analysis is further extended by utilizing an
RPBG beam, where the observed sensitivity is 21,699.26 dB/RIU
and 5846 nm/RIU, with a resolution of
4.61
×
10
−
7
, which is 2.5 times superior to the
reported results to date. By using an RPBG beam, the proposed method,
to our best knowledge, is the first to achieve much higher sensitivity
in the area of fiber optic breast cancer detection. The higher
sensitivity achieved at lower concentrations of an HER2 biomarker has
led to the idea of early diagnosis of breast cancer by optically
assessing it at its earlier stage using a high-resolution
wavelength-interrogation technique.
Subject
Atomic and Molecular Physics, and Optics,Engineering (miscellaneous),Electrical and Electronic Engineering