Affiliation:
1. Technion
2. Carnegie Mellon University
Abstract
Wavefront shaping correction makes it possible to image fluorescent
particles deep inside scattering tissue. This requires determining a
correction mask to be placed in both the excitation and emission
paths. Standard approaches select correction masks by optimizing
various image metrics, a process that requires capturing a
prohibitively large number of images. To reduce the acquisition cost,
iterative phase conjugation techniques use the observation that the
desired correction mask is an eigenvector of the tissue transmission
operator. They then determine this eigenvector via optical
implementations of the power iteration method, which require capturing
orders of magnitude fewer images. Existing iterative phase conjugation
techniques assume a linear model for the transmission of light through
tissue, and thus only apply to fully coherent imaging systems. We
extend such techniques to the incoherent case. The fact that light
emitted from different sources sums incoherently violates the linear
model and makes linear transmission operators inapplicable. We show
that, surprisingly, the nonlinearity due to incoherent summation
results in an order-of-magnitude acceleration in the convergence of
the phase conjugation iteration.
Funder
Ollendorff Minerva Center for Vision and
Image Sciences
H2020 European Research
Council
United States-Israel Binational Science
Foundation
Israel Science Foundation
Subject
Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials
Cited by
8 articles.
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