Affiliation:
1. Guilin University of Electronic Technology
2. Laval University
Abstract
The line optical tweezers (LOT) has been proven to be an alternative technique to manipulating the biological cells because of the bigger potential compared with traditional optical tweezers with a highly focused spot. We deduce the 4 × 4 optical matrix of the astigmatic LOT to investigate the optical characteristics related to the systematic parameters. The comparison of the initial and scattered electric fields by the cell under the astigmatic and stigmatic LOT is implemented to illustrate that the forward scattered light from the astigmatic LOT is much stronger than that from the stigmatic LOT, so as to the cell deformations. It is demonstrated that the astigmatic LOT could provide a more efficient way to deform the cell not only in the focal plane, but also along the optical axis to screen large biomaterials in biomechanics.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangxi Province
Scientific Research Project for Guangxi University
Guangxi Key Laboratory
Innovation Project of GUET Graduate Education