Author:
Kanae Haruki,Ito Terumasa,Tsukakoshi Kaori,Inaba Shintaro,Tomizawa Mizuki,Das Kaustav,Ikebukuro Kazunori,Misawa Kazuhiko
Abstract
Steric conformational changes in the guanine quadruplex (G4) structure due to DNA methylation are associated with cancer. We show that Raman spectroscopy can be used to detect the conformational changes in the G4 structure.