Requirement of β subunit for the reduced voltage-gated Na+ current of a Brugada syndrome patient having novel double missense mutation (p.A385T/R504T) of SCN5A

Author:

Park Na Kyeong1,Choi Seong Woo23,Park Soon-Jung4,Woo JooHan23,Kim Hyun Jong23,Kim Woo Kyung35,Moon Sung-Hwan6,Park Hun-Jun7,Kim Sung Joon18

Affiliation:

1. Department of Physiology, Seoul National University College of Medicine, Seoul 03080, Korea

2. Department of Physiology, Dongguk University College of Medicine, Gyeongju 38066, Korea

3. Channelopathy Research Center (CRC), Dongguk University College of Medicine, Goyang 10326, Korea

4. R&D Center, Biosolvix Co. Ltd, Seoul 08502, Korea

5. Department of Internal Medicine Graduate School of Medicine, Dongguk University, Goyang 10326, Korea

6. Department of Animal Science and Technology, Chung-Ang University, Anseong 17546, Korea

7. Division of Cardiology, Department of Internal Medicine, Uijeonbu St.Mary’s Hospital, The Catholic University of Korea, Seoul 11765, Korea

8. Department of Physiology & Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea

Funder

National Research Foundation of Korea

Publisher

The Korean Physiological Society and The Korean Society of Pharmacology

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