New <i>in vitro</i> multiple cardiac ion channel screening system for preclinical Torsades de Pointes risk prediction under the Comprehensive <i>in vitro</i> Proarrhythmia Assay concepta-Reference-Cited by-同舟云学术

New in vitro multiple cardiac ion channel screening system for preclinical Torsades de Pointes risk prediction under the Comprehensive in vitro Proarrhythmia Assay concepta

Published:2023-05-01 Issue:3 Volume:27 Page:267-275
ISSN:1226-4512
Container-title:The Korean Journal of Physiology & Pharmacology
language:en
Short-container-title:Korean J Physiol Pharmacol

Author:

An Jin Ryeol¹,Mun Seo-Yeong²,Jung In Kyo¹,Kim Kwan Soo¹,Kwon Chan Hyeok¹,Choi Sun Ok¹,Park Won Sun²

Affiliation:

1. Pharmacological Research Division, Toxicological Evaluation and Research Department, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Korea

2. Department of Physiology, Kangwon National University School of Medicine, Chuncheon 24341, Korea

Funder

Ministry of Food and Drug Safety

Publisher

The Korean Physiological Society and The Korean Society of Pharmacology

Subject

Pharmacology,Physiology

Link

http://pdf.medrang.co.kr/KJPP2/2023/027/KJPP027-03-267.pdf

Reference21 articles.

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4. Food and Drug Administration, HHS. International Conference on Harmonisation; guidance on S7B Nonclinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals; availability. Notice. Fed Regist. 2005;70:61133-61134.

5. Refining the Human iPSC-Cardiomyocyte Arrhythmic Risk Assessment Model