The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens

Abstract

The article presents the results of studies of the eff ect of the drug “Poledoxin”, which belongs to the group of tetracyclines and the drug “Tilmox 25%”, belonging to the group of macrolides, on some morphological and biochemical parameters of blood of Coobb-500 broiler chickens. It has been established that the use of the preparations “Poledoxin” and “Tilmox 25 %” for healthy broiler chickens according to the scheme recommended for treating birds with ornithobacteriosis and infections complicated by the causative agent of ornithobacteriosis does not cause changes in the clinical condition and behavioral reactions of the bird. A blood test found that under the infl uence of the drug “Poledoxin”, the number of red blood cells in the blood of broiler chickens increased by 4–59 % (p< 0,01) in chickens which used the drug “Tilmox 25 %” – by 5–46 % relative to control. The hematocrit value was less than the control indicator by 8 % in chickens that were treated with Poledoxin after 6 days of experiment (p< 0,05) in chickens that were used with tilmox 25 % – by 10 % (p< 0,05) through 6 and 9 days of experience. The hemoglobin content in the blood of poultry of the studied groups one day after drinking antibiotic solutions was less than the control by 7 and 8 %, respectively (p< 0,05, p< 0,01), and after 4 days – by 11 and 10 % (p< 0,01). Under the infl uence of Pledoxin, the volume of 1 erythrocyte (MCV, μm 3) in the blood of chickens was less than the control by 23–39 % (p< 0,05, p< 0,01), and when exposed to tilmox 25% – by 16–35 % (p< 0,01). The hemoglobin content in 1 erythrocyte (MCH, pg) was 62–83 % of the control index when exposed to Poledoxin (p< 0,01) and 69–86 % when exposed to tylmox 25 % (p< 0,01). The number of leukocytes in the blood of a bird under the infl uence of “Poledoxin” decreased by 8 % after a day (p< 0,01), and increased by 6 and 7 % after 3 and 4 days (p< 0,01). A decrease in the number of leukocytes in the blood of chickens of both research groups by 5–11 % (p< 0,001, p< 0,01) was established after 8 and 9 days. Key words: Poledoxin, Tilmox 25 %, broiler chickens, red blood cells, hematocrit, hemoglobin, white blood cells.