Hemocytopoiesis and microelements metabolism’s indices in calves under the infl uence of national vitamin-amino-acid complex

Author:

Melnyk A.1,Bezukh V.1,Dubin O.1,Moskalenko V.1,Vovkotrub N.1,Bogatko L.1,Tyshkivsky M.1

Affiliation:

1. Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine

Abstract

In Ukrainian veterinary medicine the study of the eff ectiveness of new complex drugs remains relevant. The eff ect of the vitamin-mineral complex "Alphabet for Animals" on the state of hemocytopoiesis and the microelements metabolism in calves of 1.5‒2.5 months of age were studied. The composition of this drug includes the biologically active substances: vitamins A, D3, E, B1, B3, B5, B6, B12, K3 and essential amino-acids: DL-methionine, L-lysine and arginine. It is used in farm animals and poultry for the normalization of hemocytopoiesis, the prevention and treatment of vitamins and trace elements metabolism’s disorders. In the fi rst week of drug administration, the number of erythrocytes in the experimental animals group has increased signifi cantly (p<0.05) and after its second feeding, the positive eff ect on erythrocytopoiesis in calves has became even greater (p<0.001), compared to the calves in control group. The level of hemoglobin in calves of experimental group also increased signifi cantly from the beginning of the drug to the end of the experiment, whereas in calves of the control group there was a tendency to decrease its level throughout the all experiment. The color index and erythrocyte saturation by hemoglobin (MCH) at the fi rst and second blood samples were signifi cantly decreased (p<0.05) in control calves group, whereas in animals of experimental group there was no signifi cant diff erence between these parameters (p<0.1). The average volume of red blood cells did not diff er between control and test calves during the experiment (p<0.1). Under the drugs infl uence the Ferum blood content in calves of experimental group increased by 24.2 %. In the control calves group, this tendency was not so noticeable (the increase of Ferum serum level at the end of experiment was only +7.8 % (p<0.1), compared to the initial indices). The Zinc metabolism, on the contrary, has not undergone signifi cant changes. The Cuprum serum level in experimental calves group remained always signifi cantly higher than in control animals group. “Alphabet for Animals” has a positive eff ect on hemocytopoiesis in calves due to its complex composition (fat-soluble and water-soluble vitamins, aminoacids) and improves the metabolism of microelements, including Ferum and Cuprum. The infl uence on these processes the vitamins of B group, which are a part of this drug, we consider especially valuable in the conditions of the unformed rumen digestion in young cattle. Key words: vitamin-amino acid complex, erythrocytopoiesis, hypochromia, microcytosis, hemoglobin, color index, hematocrit.

Publisher

The Bila Tserkva National Agrarian University

Subject

General Medicine

Reference24 articles.

1. Mel'nyk, A.Ju., Bezuh, V.M., Moskalenko, V.P., Vovkotrub, N.V., Bogatko, L.M., Shhurevych, G.O. (2018). Vplyv preparatu «Abetka dlja tvaryn» na pokaznyky erytrocytopoezu v porosjat [Eff ect of the drug "Alphabet for Animals" on the parameters of erythrocytopoiesis in piglets]. Nauk. visnyk vet. medycyny: zb. nauk. prac' BNAU [Scientifi c herald of veterinary medicine: a collection of scientifi c articles of BNAU]. Bila Tserkva, Vol. 1 (140), pp. 65–71. Available at:http://rep.btsau.edu.ua/handle/BNAU/1414.

2. Levchenko, V.I., Mel'nyk, A.Ju., Moskalenko, V.P., Bezuh, V.M., Bogatko L.M., Shhurevych, G.O., Tyshkivs'kyj, M.Ja., Sakara, V.S. (2017). Vplyv preparatu Gep-A-Stres na obmin rechovyn u kurchat-brojleriv [Eff ect of the drug Gep-AStress on the metabolism of chicken-broilers]. Nauk. visnyk vet. medycyny: zb. nauk. prac' BNAU [Scientifi c herald of veterinary medicine: a collection of scientifi c articles of BNAU]. Bila Tserkva, Vol. 1 (133), pp. 48–55. Available at:http://rep.btsau.edu.ua/handle/BNAU/1415.

3. Levchenko, V.I., Mel'nyk, A.Ju., Bezuh, V.M., Moskalenko, V.P., Harchenko, A.V. (2016). Vplyv preparatu Megavit na A-vitaminnyj i kal'cije-fosfornyj obmin u sil's'kogospodars'kyh tvaryn [Eff ect of Megavit on A-Vitamin and Calcium-Phosphorus Exchange in Farm Animals]. Nauk. visnyk vet. medycyny: zb. nauk. prac' BNAU [Scientifi c herald of veterinary medicine: a collection of scientifi c articles of BNAU]. Bila Tserkva, no. 1 (127), pp. 49–56. Available at:http://rep.btsau.edu.ua/handle/BNAU/289.

4. Levchenko, V.I., Mel'nyk, A.Ju., Moskalenko, V.P., Bogatko, L.M. (2015). Efektyvnist' preparatu Ferolajf za gipoplastychnoi' anemii' porosjat i teljat [Effi ciency of the Ferolift drug for hypoplastic anemia of pigs and calves]. Nauk. visnyk vet. medycyny: zb. nauk. prac' BNAU [Scientifi c herald of veterinary medicine: a collection of scientifi c articles of BNAU]. Bila Tserkva, no. 2, pp. 46–54. Available at:http://rep.btsau.edu.ua/handle/BNAU/283.

5. Levchenko, V., Bohatko, L., Bezukh, V., Moskalenko, V., Melnyk, A. (2016). Novi preparaty dlja likuvannja okremyh vnutrishnih hvorob tvaryn [New drugs for the treatment of individual internal diseases of animals]. Zdorov’ja tvaryn i liky [Health of animals and medicine]. no. 2, pp. 14–18. Available at:http://rep.btsau.edu.ua/handle/BNAU/296.

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