Affiliation:
1. FSBI “National Medical Research Radiological Center" of the Ministry of Health of the Russian Federation
2. SBIH “Hospital for war veterans № 2 "
3. FSBEI HE “Lomonosov Moscow State University"
Abstract
Xenon is an inert gas used like inhalational anesthetic during different surgeries, including high-risk operations and for pain treatment caused by different factors. If concentration of the gas is less than 50 %, or the duration of the procedure is very short, no consciousness depression occurs. 20 healthy persons from 22 to 30 years old were undergone xenon/oxygen inhalation with concentration 70/30 % respectively for 3 minutes. Electroencephalography (EEG) was recorded before, during and 30 minutes later the procedure. For the data processing spectral analysis was used. Statistical analysis was performed by Wilcoxon and Page tests. As a result, significant increase in slow wave activity and reduction in alpha-rhythm activity were observed during and after the procedure as well as repartition of activity zones in brain similar to physiological sleep. This fact may be used in conduction of treatment and diagnostics procedures.
Publisher
Practical Medicine Publishing House
Reference14 articles.
1. Буров Н.Е., Потапов В.Н. Ксенон в медицине: очерки по истории и применению медицинского ксенона. М.: Пульс, 2012
2. Lu Tian Liu, Yan Xu, Pei Tang B. Mechanistic Insights into Xenon Inhibition of NMDA Receptors from MD Simulations. J Phys Chem. 2010; 114(27): 9010-9016.
3. Petrenko A.B., Yamakura T., Sakimura K., Baba H. Defining the role of NMDA receptors in anesthesia: are we there yet? Eur. J. Pharmacol. 2014; 15(1): 723: 29-37.
4. Рылова А.В., Лубнин А.Ю. Динамика внутричерепного давления во время ксеноновой анестезии у нейрохирургических больных без внутричерепной гипертензии. Анестезиология и реаниматология. 2011; 4: 13-17.
5. Козлов И.А. Ксенон при кардиохирургических операциях. Комплексный анализ. Вестник интенсивной терапии. 2007; 3: 45-53
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献